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QSART Testing: Essential for Autonomic Neuropathy Diagnosis

What is QSART:

Quantitative Sudomotor Axon Reflex Test (QSART) is a test to evaluate the integrity of the postganglionic sudomotor system along the axon reflex to define the distribution of sweat loss. This is accomplished by the release of acetylcholine into the skin which activates receptors on the eccrine sweat gland. The sweat response is recorded from four sites (forearm and 3 lower extremities sites) and assessed for deficits.

What does it measure:

The QSART is a test that measures the autonomic nerves that control sweating. The test is useful in assessing autonomic nervous system disorders, peripheral neuropathies and some types of pain disorders. The test requires a mild electrical stimulation on the skin called iontophoresis, which allows acetylcholine, a naturally occurring chemical, to stimulate sweat glands. The QSART measures the volume of sweat produced by this stimulation.

QSART is used to diagnose:

Painful, small fiber neuropathy when nerve conduction test results are normal
Disturbances of the autonomic nervous system, which controls the sweat glands, heart,
digestive system, other organs, and blood pressure
Complex pain disorders
Diabetic neuropathies
Enzyme disorders
RSD (Reflex Sympathetic Dystrophy, Complex Regional Pain Syndrome)
Dysautonomia
Multiple System Atrophy (Shy-Drager syndrome)

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FAQ

Frequently Asked

LET'S TALK

+ What is QSART?

Intellewave is a diagnostic device designed to perform comprehensive autonomic nervous system (ANS) testing, providing an alternative to the RM-3A. It helps healthcare providers evaluate various health parameters, including cardiovascular function, metabolic health, and nervous system balance.

+ What conditions can QSART diagnose?

QSART is commonly used to diagnose conditions related to autonomic neuropathy, such as diabetic neuropathy, small fiber neuropathy, and other disorders that affect the sweat glands and nerve function.

+ How does the QSART test work?

QSART involves the use of electrodes that stimulate the sweat glands with a mild electrical current. The response of the sweat glands is then measured to evaluate nerve function. This test helps determine how the autonomic nervous system is functioning.

+ Is QSART testing safe?

Yes, QSART is a safe and non-invasive test. The electrical stimulation used is mild and generally well-tolerated by patients.

+ What can I expect during a QSART test?

During the QSART test, small electrodes are placed on the skin, usually on the forearm, leg, or foot. A mild electrical current stimulates the sweat glands, and the amount of sweat produced is measured. The test typically takes about 30-45 minutes to complete.

+ Is the QSART test painful?

Most patients report only a slight tingling or warm sensation during the test. It is generally considered painless, though some may experience mild discomfort from the electrical stimulation.

+ How do I prepare for a QSART test?

Preparation is minimal. Patients are usually advised to avoid applying lotions or creams to the skin before the test and may be asked to avoid caffeine or smoking on the day of the test. Your healthcare provider will give specific instructions based on your condition.

+ How are QSART results interpreted?

QSART results are interpreted by comparing the amount of sweat produced in response to the stimulation. Abnormal results may indicate issues with the autonomic nervous system or nerve damage affecting sweat glands.

+ Where can I get a QSART test done?

QSART testing is available through healthcare providers equipped with the necessary technology. Physicians Options offers the QSART device for clinical use, and you can contact their team for more information on purchasing or finding a facility that provides this test.

QSART – Quantitative Sudomotor Axon Reflex Test